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Does endometritis affect implantation or miscarriages?

1 fertility expert(s) answered this question

How does endometritis impact embryo implantation and the risk of miscarriage?

Endometritis, an inflammation of the uterine lining, can negatively impact embryo implantation by disrupting the receptive environment required for the embryo to attach. It may lead to an abnormal immune response, affecting embryo development and increasing the risk of miscarriage due to inflammation and potential infection.

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Answer from the fertility expert:
Elias Tsakos, Medical Director, EmbryoClinic

Both. I believe that many of you may have experienced some form of endometritis, whether you knew about it or not. Research data shows that treating endometritis results in a fivefold higher ongoing pregnancy rate and live birth rate, which is quite significant. Additionally, there is an 80% reduction in miscarriage rates. Clearly, this is an issue that we need to address. Observation number one is that the treatment of endometritis has a significant positive effect on IVF outcomes. In cases where endometritis is cured, there is no statistical difference, which is quite interesting. The key takeaways are that endometritis is a localized inflammatory response within the uterine cavity caused by microorganisms. It is a common condition, particularly in women with infertility and multiple failed IVF attempts.

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