With egg donation program, in most of cases, probably there is no need because the percentage of genetically abnormal embryo is not high but if, for example, woman has several spontaneous abortion, if, for example, husband has very poor sperm quality, if they have done egg donation before and it didn’t work with good normal endometrium, then yes, it may be helpful.
Using any kind of genetic screening to check embryos that are coming from egg donation, it’s not proven to be necessary all the time. Unfortunately, some clinics may routinely offer this but let’s think about it, the eggs are young, these are young, healthy eggs that are being used, so as long as the sperm is normal. The research doesn’t show any benefit to add any kind of genetic screening for those embryos. The concern comes in if we have also got some issues with the sperm, so if the sperm, for example, has got high uneuployed rates or abnormality rates, chromosome unemployed rate, it can be beneficial maybe if needed in the previous IVF cycles it’s been shown that there has continuously been a very poor development of embryos or many miscarriages, then it could be beneficial but routinely it is really not needed if the sperm quality is good and the egg equality from a young donor is also good, that there is no need to do it.
There are not many papers out there but two or three say that this does not help at all. Most of the papers show the donor eggs come from younger women so we take out the factor that really aids the egg and tends to create chromosome abnormalities. When we take out this factor we don’t really have a good indication to take this test. However there are some labs in the United states that are performing this test in donor eggs but most of these trials don’t show any benefits from it.
