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What is the difference between PGS and PGT-A?

1 fertility expert(s) answered this question

Is there difference between PGT-A and PGS?

How the technic evolved during the time and what impact it my have on pregnancy rate?

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Answer from the fertility expert:
Dimitra Christopikou, Head of the PGT lab, Embryogenesis IVF Unit Athens

There is no difference, it is the same name and what it used to be called as well as the more modern name. We used to call it PGS, preimplantation genetic screening, now we call it preimplantation genetic testing for aneuploidy. However what is different is the technique and both the techniques of the biopsy and genetic analysis have changed. I was involved in this, in previous years and due to my experience I had the privilege of going through these techniques that require more skill such as fixation of cells. We used to test only one cell on day 3, one blastomer on day 3, this caused a lot of problems and we used to only analyse genetically from nine to thirteen chromosomes. Nowadays we do cubing, it is better than fixation, we don’t use loose chromatin or DNA and we analyse the complete set of chromosomes, so twenty three pairs so we have evolved. PGT and PGTA are far better than PGS but it is the same name for the same process.

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Can I see results – report from PGT-A / PGS tests?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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Can I use PGT-A / PGS for gender selection?

Nurit Winkler,
Gynaecologist

+ 1 more answers

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Can PGT-A / PGS detect autism?

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+ 1 more answers

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Raúl Olivares, MD
Gynaecologist

+ 1 more answers

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Does PGT-A / PGS reduce miscarriage risk?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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How many embryos should you PGT-A / PGS test?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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How many embryos should you have for PGT-A / PGS test?

Raúl Olivares, MD
Gynaecologist

+ 1 more answers

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How many embryos survive PGT-A / PGS testing?

Raúl Olivares, MD
Gynaecologist

+ 1 more answers

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How many PGT-A / PGS normal embryos miscarry?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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What are the pros and cons of using PGT-A / PGS testing on embryos?

Raúl Olivares, MD
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+ 1 more answers

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How often do PGT-A / PGS tested embryos fail?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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Can PGT-A / PGS detect gender of an embryo?

Nurit Winkler,
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+ 1 more answers

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How much does PGT A PGS testing cost?

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Should PGT-A / PGS be used to test embryos developed from donor’s eggs?

Halyna Strelko, MD
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+ 2 more answers

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What percentage of embryos pass PGT-A / PGS testing?

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Geneticist

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Why do PGT-A / PGS embryos fail?

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How accurate is PGT-A/PGS?

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Should I transfer 1 or 2 embryos after PGS?

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What single gene mutations/defects can be diagnosed with PGD?

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