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On what day are embryos biopsied for PGT-A?

Category: (PGT) Preimplantation Genetic Testing (PGT-A, PGT-M, PGT-SR)

1 fertility expert(s) answered this question

At what stage of development are embryos typically biopsied for PGT-A?

On which specific day during the embryo’s development process, a biopsy done through PGT-A testing is typically performed?

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Answer from the fertility expert:

Raúl Olivares, Medical Director & Owner, Barcelona IVF

According to published studies, biopsies should always be conducted on day 5 at the blastocyst stage. For many years, biopsies were performed on day 3 under the assumption that it was a safe procedure. However, some studies confirm that conducting the biopsy on day 3 could reduce the implantation potential of these embryos by up to 40%, which doesn’t occur when the biopsy is done on day 5. Therefore, nowadays, all biopsies should be conducted at the blastocyst stage.

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