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What are the pros and cons of using PGT-A / PGS testing on embryos?

2 fertility expert(s) answered this question

Who should consider genetic testing?

Genetic tests identify changes in your genes, chromosomes, or proteins. The results of such tests can confirm or rule out a suspected genetic disease or help pinpoint your chances of developing a disease or passing it to your future children. What other factors might be essential to consider genetic testing?

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Answer from the fertility expert:
Raúl Olivares, Medical Director & Owner, Barcelona IVF

I think that there are mostly pros when using PGT-A, with perhaps the only drawback being that this technique is quite new. As a result, we are not completely sure about the long-term effects of the biopsies on babies born after undergoing PGT-A. That’s why we usually don’t recommend PGT-A in all cycles, only in those where there’s a medical indication for it. However, the benefits of the information we obtain outweigh any potential future risks associated with the technique.

Answer from the fertility expert:
Dimitra Christopikou, Head of the PGT lab, Embryogenesis IVF Unit Athens

In my personal opinion, the advantage is you can discriminate and pick through, the screening process, the embryo that will give you a live birth because the most important fact is that when you go through the IVF procedure the pregnancy rates matter but what matters most is the live birth. When you are a patient what you are looking for after IVF is a healthy baby, a live birth and a healthy baby at home. In my opinion, this is the advantage of the whole process. However if you have a few or bad looking embryos that don’t develop well there is no reason to undertake this type of process. If you don’t have any indications, if you are not older than thirty eight or forty years, have recurrent miscarriages, or repeated IVF failures or if you are really young I don’t think this type of procedure will help you. The disadvantage of this procedure is that it will not increase the chance of having a pregnancy. Even if you don’t do it you will have a pregnancy but the benefit is it will increase your chance of delivering a healthy baby without miscarrying it.

Can embryo biopsy damage the embryo?

Raúl Olivares, MD
Gynaecologist

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What is the PGT-A strategy for patients with implantation failure?

Raúl Olivares, MD
Gynaecologist

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On what day are embryos biopsied for PGT-A?

Raúl Olivares, MD
Gynaecologist

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How can PGT-A reduce the time to pregnancy?

Raúl Olivares, MD
Gynaecologist

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How can PGT-A improve embryo selection?

Raúl Olivares, MD
Gynaecologist

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Can I see results – report from PGT-A / PGS tests?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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Can I use PGT-A / PGS for gender selection?

Nurit Winkler,
Gynaecologist

+ 1 more answers

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Can PGT-A / PGS detect autism?

Maria José Mendiola, MD, MSc in Human Genetics, MSc in Science Communication, ObGyn
Gynaecologist

+ 1 more answers

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Can you do a fresh embryo transfer with PGT-A / PGS?

Raúl Olivares, MD
Gynaecologist

+ 1 more answers

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Does PGT-A / PGS reduce miscarriage risk?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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How many embryos should you PGT-A / PGS test?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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How many embryos should you have for PGT-A / PGS test?

Raúl Olivares, MD
Gynaecologist

+ 1 more answers

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How many embryos survive PGT-A / PGS testing?

Raúl Olivares, MD
Gynaecologist

+ 1 more answers

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How many PGT-A / PGS normal embryos miscarry?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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What is the difference between PGS and PGT-A?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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How often do PGT-A / PGS tested embryos fail?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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Can PGT-A / PGS detect gender of an embryo?

Nurit Winkler,
Gynaecologist

+ 1 more answers

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How much does PGT A PGS testing cost?

Maria José Mendiola, MD, MSc in Human Genetics, MSc in Science Communication, ObGyn
Gynaecologist

+ 1 more answers

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Should PGT-A / PGS be used to test embryos developed from donor’s eggs?

Halyna Strelko, MD
Gynaecologist

+ 2 more answers

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What percentage of embryos pass PGT-A / PGS testing?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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Why do PGT-A / PGS embryos fail?

Dimitra Christopikou, Clinical Laboratory Geneticist
Geneticist

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Can you avoid Down syndrome with IVF?

Glykeria Samolada, Biologisst, MSc. Mol. Cytogenetics
Geneticist

+ 4 more answers

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How accurate is PGT-A/PGS?

Maria José Mendiola, MD, MSc in Human Genetics, MSc in Science Communication, ObGyn
Gynaecologist

+ 3 more answers

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Should I transfer 1 or 2 embryos after PGS?

Maria José Mendiola, MD, MSc in Human Genetics, MSc in Science Communication, ObGyn
Gynaecologist

+ 3 more answers

Read More »

What single gene mutations/defects can be diagnosed with PGD?

Maria José Mendiola, MD, MSc in Human Genetics, MSc in Science Communication, ObGyn
Gynaecologist

+ 3 more answers

Read More »
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