Theoretically, there are cases in which we can perform a fresh embryo transfer after conducting genetic testing on the embryos (PGT-A). However, this is something that we usually do not recommend. If you want to proceed with a fresh embryo transfer, the biopsy should ideally be done on day 5, and the results should be available on day 6. Since embryos can also be tested for genetics on day 6, this sometimes means that patients may end up with embryos that have been biopsied on both day 5 and day 6. Some of these embryos may be normal, while others may be abnormal. In these cases, it’s quite common for patients to have to pay for 2 different PGT-A rounds: 1 for the embryos intended for the fresh embryo transfer and another round of testing for embryos that will be transferred later, which are biopsied on day 6. Although it is technically possible, we usually recommend performing the biopsy of all embryos on both day 5 and day 6. Once we receive the final results, we can consider which embryos should be transferred.
Yes you can, in very busy labs that can apply NGS on a daily basis but I do not know if this is feasible for big labs that apply NGS for chromosome analysis of pre-implantation embryos. However, I would not recommend a first embryo transfer as in our hands at least we have seen, and there are many reports out there, that when you transfer an embryo back on day 6 or day 7 of embryo development in a uterus of a woman that has been stimulated, then the endometrium) might be out of phase and you will have lower pregnancy rates. So you don’t benefit from fresh embryo transfers and most of the time the embryos don’t implant even if they are normal as you will miss the window of implantation. However, I think it is feasible with the latest NGS technique but in very big genetic labs.
