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Is egg quality connected with genetics?

3 fertility expert(s) answered this question

Is poor egg quality genetic?

Studies proved that the number one factor that affects egg quality is age. We expect poor quality of eggs in women after oncological treatment whether it was chemo or radiotherapy. Immunological issues also affect fertility but it is not confirmed if it actually influences the quality of eggs.
Aneuploidy is a result of abnormal chromosome structure but would that be with one’s genetics directly?

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Answer from the fertility expert:
Elena Santiago, Fertility Specialist, Vida Fertility Institute

Egg quality is affected by genetics. Factors such as chromosomal abnormalities or mutations can affect egg health and development. Genetic influences are related to egg quality and may cause a higher risk of miscarriages and aneuploid embryos, meaning they will have chromosomal disorders, especially as the woman ages.

Answer from the fertility expert:
Lucy Lines, Business Owner at Two Lines Fertility

In some instances yes, you might have a genetic predisposition to just making crappy eggs for a wonderful better term and there’s nothing you can do about that. You don’t know that until you make some of the dietary and lifestyle changes to see if that has an impact. I recommend everybody do that before they start any kind of IVF – so that when they present those raw materials to the lab, they’re the best they can be.
Is it connected with genetics? Yes, it definitely can be but does it then go on to pass on genetic problems to the baby?Really – probably not.

Answer from the fertility expert:
Saghar Kasiri, Director of European Operations, Cryos International

Some genetic diseases can impact the quality of the eggs and the number of eggs that are available in the ovaries and as a result women that may have that particular genetic disease could end up not producing enough eggs or producing eggs that are of poorer quality.

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