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Egg donor genetic matching – how does it work?

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1 fertility expert(s) answered this question

How does egg donor matching work?

Egg donor matching is a process used in assisted reproductive technology to select an egg donor whose genetics match those of the egg recipient. This matching is very important because it can increase the chances of a successful pregnancy and the birth of a healthy baby. So how does egg donor genetic matching work?

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Answer from the fertility expert:
Laura García de Miguel, Fertility Specialist, Clinica Tambre

Genetic matching is a possible process that we offer for egg donation treatments. It consists of doing a previous DNA blood or saliva test in both, the donor and the recipient, the man, and we will check, in around 300 conditions, if they are carriers of any of these mutations or not. In the event of the husband being a carrier, then the donor that would be selected in regards to the physical characteristics of the future mother and will be confirmed by the lab if it’s a correct match which means that they are not sharing any mutations. If by contrast, the selected donor is incompatible with the man, this means that they are carrier of the same mutation and they have a risk of transmitting the disease to the baby. So then, this donor will be refused, and we will start the process with a new donor.

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