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What are the chances of getting pregnant with frozen eggs?

Category:
4 fertility expert(s) answered this question

What are the success rates of IVF with frozen eggs?

IVF treatment can be carried out with fresh eggs or with frozen eggs. Do your chances differ if you use cryopreserved oocytes?

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Answer from the fertility expert:
Ahmed Amer, Senior Embryologist, ARGC Limited

Chances of getting pregnant with frozen eggs are lower than chances of getting pregnant with the fresh eggs. This is because of the process of freezing and thawing which is a significant milestone eggs have to go through. As a result, the live birth rate from frozen eggs is about 18 to 19% per embryo transfer cycle compared to 26 to 27% when you use fresh eggs. That significant difference is down to the freezing & thawing process.

Answer from the fertility expert:
Jessica Subira, Fertility Specialist, IVI RMA Global

Well this very much depends on the clinic and this is something that you always have to ask your specialist, your doctor when you talk about it. Just to give you an idea of how it works here at IVI RMA. We know that for young patients below 35, if we have a good number of eggs stored like between 10 -15, as we mentioned before, then we will get a chance of between 50-60% chance of a live birth thawing them and fertilizing them. For us is a very good chance of course if we as we mentioned before we always have to take into account what we call the cumulative pregnancy rate that means not only using the first embryo that we get from the eggs but also using the rest of the embryos that can have been frozen as a result of the first egg thawing. If we take into account cumulative pregnancy rates we can go up to even 80-90 % of cumulative live birth rate when we have 20 -25 eggs frozen from a young woman. Usually  above 35 or especially 38 ,we know that the chances of having a pregnancy will be reduced but still if we have a good number of eggs, we can get something in the region or between 30-50 % if we have uh 15 eggs or so frozen from them. This very much depends on the clinic so let me give you a rough estimation and this is something that you have to discuss and ask your specialist to show you the success rate.

Answer from the fertility expert:
Melvin H. Thornton, Medical Director & IVF Director, Global Fertility & Genetics

For the clinic, there is no difference in using frozen or fresh eggs. Here in the US, there has been a lot of what we call frozen donor egg banks. Whereas before we always use fresh donor eggs but now there are a lot of egg banks out there that will have donors come in and freeze the eggs so that individual clients can use individual frozen eggs and sometimes they get a lot, six to eight. With frozen donor eggs theoretically, the success rates are the same as the fresh ones, but the success rates may be slightly lower with the frozen donor egg, but nothing significant to where we would not encourage a woman to freeze her eggs for future fertility.

Answer from the fertility expert:
Ioannis Zervomanolakis, Hygeia IVF Athens

The chances of getting pregnant with frozen eggs are quite similar to those of fresh eggs since the quality of oocytes is not affected by vitrification. Regarding the eggs of the patients during egg freezing a patient under 35 has a chance of around 50-60% to get pregnant immediately. While a patient over 35 has a lower chance. That has to do with their age group. It means women under 40 have a chance of around 40% to get pregnant, while this chance is lower when a woman is over 40 during egg freezing.

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