That’s a tough one because you have been through a lot and you have listed pretty much everything that we have mentioned including the ERA test, hysteroscopy, thrombophilia, NK blood test, biopsy. I did have a patient who has been through 19 cycles including some with egg donation and the spermiogram looked perfect. It was normal and, eventually, because there was no other answers, she said “well, what can you recommend?” and I said “well, the only actually binding issue putting all these cycles together is the sperm cells. They were always the same and even though this spermiogram looked really strong, we performed a DNA fragmentation test and it showed actually a very high level of DNA fragmentation. Back at that time, we didn’t have the MACS test to sort out the sperm cells prior to fertilization so I recommended donated sperm and she got pregnant and carried successfully to term. That was the game-changer, eventually. But, here, this is too simple of an answer and it doesn’t really hit it correctly. Five donor egg transfers – grade 1 embryos, one embryo each time. This is really tough. We’re looking at the two frozen embryos, of course. At 48. I don’t really recommend usually in a natural transfer cycle a native frozen embryo transfer cycle even if the cycle is still quite regular. I would give those two remaining embryos a chance and then eventually think about adoption. I’m sorry, it’s really tough but I don’t see any loopholes here I mean you have done everything right. I’m very sorry and it hurts but I don’t have an answer. The one with termination doesn’t really play a role. The natural pregnancy with the same partner that ended in miscarriage doesn’t really change it. At 45, everybody’s saying okay, the major suspect here is the quality of the eggs and, yes, rightly so. But the sperm quality can also play a role and the fragmentation can be a part of that so that’s maybe something to look into. But it’s not going to play a role in the transfer of those frozen embryos, you’re not going to change anything there so I would just give them a chance and that’s it.