A lot of my colleagues would disagree with me, so once again, it’s possible my opinion does not reflect the concept of all the other clinicians. We have a certain number of patients that varies between 3 to5 %, that seems small, actually, it is 1 out of 20 including the couple, 1 out of 30 that have some chromosomal abnormalities, and that could affect the implantation, could affect the results of IVF. The question I ask myself and I ask the patients is always the same. In Italy, at least in Italy, chromosomal analysis costs around 100 EUR, and it lasts forever, I mean it’s like to have the blood group, it will not change in your life, and it lasts forever. I’m not advocating to do all these things to everybody, but I would like to have one dinner less, one new jumperless, but having done this exam before the beginning of all my infertility treatment and the reason is very simple. If after 3, 4, 5 failed IVF attempts or ICSI, somebody suggests me to do a chromosomal analysis, and it turns out that I am one of those 1 in 30, 1 in 50, it doesn’t matter, that has a problem, that has an explanation why it was not successful, I’m going to strangle my clinician, I am going to strangle myself, as those 100 EUR, one blood sample which will be valid all your life. When you say PCOS is your only infertility reason, it’s wrong, it could be the only fertility reason. How do you know that your husband has not a chromosomal rearrangement or yourself have not a chromosomal rearrangement, maybe a simple piece of chromosome that doesn’t change at all your life, it makes you perfectly sane, but it reduces the quality of your oocytes.