Watch the webinar with Dr Irina Kotsiubska, an obstetrician-gynaecologist, fertility specialist in Assisted Reproductive Technologies at Parens, Ukraine, and find out how to have a successful IVF treatment after failed attempts.
You received 5 good quality embryos. In our clinics, we very often use embryos of AA, but during our practice, sometimes, it’s better to receive the embryos of 4BB because remember that an embryo of 5AA is very hard to get, and not all can give us the implantation. Sometimes when we see a good quality embryo, the genetic analysis might not be good even if we have 5AA embryos. About, CC embryos, those are of very low quality, and very rarely they can give us pregnancy. It’s better to do a transfer with embryo 3 or 4 BB or 5 BB or BA, such embryos, can give us a pregnancy.
It depends on the stage of your endometriosis. If it isn’t too severe, there is no difficulty in your uterus, it shouldn’t be a big problem for receiving a pregnancy. First of all, I would like to ask you if you ever did a hysteroscopy, and if everything was okay during hysteroscopy, you can try again to do a transfer. If everything is okay with your endometrium, I don’t think that endometriosis will be a big problem because, in our practice, a lot of patients with this disease receive their own pregnancy after an IVF program. It depends on a hysteroscopy picture, and I would like to see your hysteroscopy results if you’ve ever done this.
In your case, I would advise you to do another donor program. It might be better to take another donor. Maybe you have had some problems with sperm analysis of your husband because if you use a donor, you would have received more good embryos, 2 or 3 embryos. In general, when we receive eight eggs, we receive a good blastocyst by 40%. In this case, I would like to see a sperm analysis of your husband.
When it comes to supplements, we always prescribe folic acid and vitamin E, Omega-3, and vitamin D. When it comes to other vitamins, it would be better to take it one month or three months before pregnancy, a lot of various vitamins are available, and you can find them in different countries. We don’t prescribe folate, we prescribe folic acid.
I prefer nospa or papaverine, but it depends on the week. If we speak only after a transfer, it will be better to use only Magne B6, it will be enough, and when we have some problems after a transfer, in this case, we’ve just got another medication like Nospa, or some other ones.
We also use EmbryoGlue, and in my opinion, it is very good. We use this culture for the patients who are over 35 when we receive few embryos or few oocytes, and if you’ve had unsuccessful IVF treatment before.
No, we don’t perform such transfers at our clinic.
If it’s only a problem with a low sperm count, we can propose a tandem program, using your husband’s sperm and from donor sperm. We could also suggest doing a PGT analysis of your blastocyst using sperm from your husband. If you have a good quality blastocyst, a genetic test might still be good because you might see a good quality blastocyst, but still, you might be receiving not a very good genetic analysis. We can propose a genetic analysis or using a tandem program.
If we speak about the IVF cycle, during stimulation, we monitor progesterone levels and estradiol levels. We need to decide if we do transfer in the same cycle or if we need to do transfer in the next menstrual cycle. When we do the transfer, in the next menstrual cycle, sometimes we prescribe progesterone, if it’s necessary, it all depends on each patient’s history, and we start it during the preparation of the endometrium or after embryo transfer. If we think that you can have a low progesterone level after embryo transfer. When it comes to patients from abroad before the program, during the program, we always speak with our patients, either by mail, messenger, WhatsApp, and we give them our recommendation or prescription during the whole program and during pregnancy.
Yes, sometimes, I recommend steroids to patients who have multiple sclerosis to help the implantation, but it depends on the patient. There are many other medications that we prescribe in this case.