There are a lot of things here that would require a proper consultation. It wouldn’t be right to comment on your case just from this information. By any means, let me try to tell you a few things. We know that there is a translocation in your husband’s karyotype, this is an important factor, and in such case, PGT-SR is required, and many times we need to have a lot of blastocysts, only to find one that is chromosomally normal and will get implanted. This can also be a reason for the failure of implantation. The fact that you produce that many eggs at the age of 35, shows that perhaps you had also PCOS in the past because it is a very big amount of eggs, which is not bad in your case, because we need many eggs to get chromosomally normal embryos. Since the hydrosalpinx had been removed, and you’ve done hysteroscopies and laparoscopy as well, I am not sure if implantation failures only depend on the endometriosis or not, but it is possible. Because of your history, and unexplained failure of implantation, I would advise to down-regulate you with GnRH injections before a frozen transfer so that we can suppress any disease, perhaps that would increase the chances of implantation. In many cases, it is associated with immunological issues, it is not clear if you’ve done any natural killers etc., but I would cover you with some immunosuppression as well. After embryo transfer like intralipids or steroids. Endometriosis is associated with some problems with endometrium, with the lining of the womb, implantation. We do see local inflammation from endometriosis on may occasions, sometimes we do suggest some antibiotics as well before embryo transfer, especially if there is an element of endometritis as you’ve mentioned. If the previously failed transfer was unexplained, I would also suggest an ERA test, to make sure that the implantation window is right or not. I cannot confirm that endometriosis is definitely the reason for failed implantation but since you know you have endometriosis GnRH as I’ve said, might help.