According to the international morphological trading – 3BB embryo is a good one. But as I had told you, at the beginning of presentation there is a very slight correlation between this external appearance and genetic competence, and for sure 3BB embryo can have 40% of being genetically normal. There is a correlation with age, in most cases, the patient who is 43 years old will have lower chances than women who is 39. However, it’s not that simple because we should take into the account, AMH level, the number of antral follicles by ultrasound. The general somatic status because a reproductive area is not a separate system in our organism. If a woman has some diseases or she has to take medication which can affect the quality of eggs. Unfortunately, at times, we do not obtain a good embryo even in very young patients, f. e. in patients has a kidney condition, they need to take very harmful medications, that will influence the quality of the embryos. Also, some immunological diseases like endometriosis – it can affect the quality. If, we are talking about the embryo arrest, which means that the embryo stops growing properly. It usually is associated not only with egg quality but also with sperm quality. We need to examine both partners. I would need more information form you on how many follicles were obtained if you had surgeries on ovaries and a little bit more about medical history.
When it comes to the difference between the natural cycle and the frozen cycle. There were plenty of trials comparing the results in outcomes of a natural cycle and frozen cycles. Most of these were done on a large number of participants. It demonstrated that there is no difference in the outcome, however, you should take into the consideration that in natural cycles, we do not prescribe any hormonal medication, during the protocol for hormonal replacement therapy we have to prescribe some kind of hormones and this causes huge stress in the organism. Sometimes a patient has contraindications that do not allow us to prescribe this medication. In this mode of the natural cycle, it will be the first-line therapy. I prefer to make everything more natural, and even when we have a very strong standardized protocol for each situation, I always tell my patients that less is more and, in medicine, we should avoid additional interventions. When we can make a natural cycle and frozen embryo transfer, we can do it. If we are talking about egg retrieval in natural stimulation or ovarian stimulation, we have a lot of arguments that egg retrieval in ovarian stimulation cycle is much better.