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None of the embryos were tested in my donor cycles. I have two 6BB embryos left. Would they be considered good to transfer?

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Esther Marbán, MD

I’m 49, about to do my 5th donor IVF cycle with the 3rd donor. The first cycle resulted in a chemical pregnancy. My BMI was over 30 for all cycles. The cycle will include an ERA test. Would you recommend a hysteroscopy at the same time as the ERA test? I am on medication for hypothyroidism and have one ovary and blocked fallopian tubes. I have gone through menopause but have been on progesterone for 3 months. Any advice you can give to increase the odds of success?

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Esther Marbán, MD

I’ve had two rounds of stimulation with low follicle counts. I’m 41 and have stage 4 endometriosis. Should the stimulation protocol be changed?

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Elias Tsakos MD, FRCOG

I have high thyroid antibodies and my thyroid function blood test is within the normal range. How should this be approached before or during IVF?

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Elias Tsakos MD, FRCOG

What about the treatment of Ureaplasma found in a random culture of asymptomatic vaginal smear? Should we treat it?

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Elias Tsakos MD, FRCOG

If you have had a hysteroscopy previously, do you need to repeat it if it was done 8-10 years ago and you’ve had multiple IVF attempts since then?

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Elias Tsakos MD, FRCOG

What is the impact of BMI on the IVF protocol? Does the medication get more diluted, making it less effective in terms of stimulation?

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Elias Tsakos MD, FRCOG

What would you suggest for recurrent implantation failure? I’ve had a biopsy, laparoscopy, ERA, thrombophilia and thyroid tests done. A total of 40 embryo transfers, four PGT-tested embryos, two blastocysts, and 41 trying since I was 34. 4 clinics in 3 countries.

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Elias Tsakos MD, FRCOG

In my hysteroscopy, there was a possibility of adhesions but not certainty. At the same time, my endometrium is always between 7-11 mm at the moment of ovulation. Does such an endometrium exclude adhesions in your opinion? Can adhesions prevent implantation? From your experience, how big is the improvement achieved by PRP? I’m 41 but already at age 36, my testosterone was practically zero. How many failed IVF cycles are too many? I’ve had several complete fertilization failures and empty follicles. I’ve had 8 already, all with high stimulation doses.

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Elias Tsakos MD, FRCOG

What to do if factor VIII (only this one) is above the norm, and doctors say it’s not a mandatory sign for thrombophilia?

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Elias Tsakos MD, FRCOG

What grade of cervical pathology would be acceptable for IVF? What about HPV? Is it possible to go through IVF with a positive HPV result?

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Elias Tsakos MD, FRCOG

What kind of simulation protocol do you recommend for older women with PCOS? Do you use Clomid or Femara? I’m 51, but my FSH is still 5.6 nanograms per millimeter, LH is 4.4, prolactin is 64.4, estral is 111.6, and I don’t have high testosterone. My last AFC was 26. I get a lot of eggs with FSH-only protocols, but they are immature. Last round I did estrogen priming and added LH to the protocol, but got only four eggs, two of them fertilized, and only one blastocyst.

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Elias Tsakos MD, FRCOG

Where can I have IVF treatment with no age limit, and what does the situation look like in Ukraine, for example?

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Halyna Strelko, MD

When collecting follicles, would you prefer a natural or stimulated cycle?

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Halyna Strelko, MD

Does artificial testosterone help develop more and better follicles?

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Halyna Strelko, MD

How much melatonin should I take per day, and which type of melatonin should I choose?

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Dorothy Walas

Is there a fluctuation in FSH, AMH, or TSH levels depending on the day of the blood test?

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Halyna Strelko, MD

Why do ovaries stop the normal growing process of follicles under stimulation therapy, which aims to stimulate growth? The body reacts the opposite way it should. Are there specific conditions when ovaries stop growing?

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Halyna Strelko, MD

Are there any other options, in addition to PRP method, to increase the ovarian response? Maybe taking antral follicles and growing them in controlled conditions?

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Halyna Strelko, MD

Is there a possibility to figure out the ovarian sensitivity to FSH and AMH, or improve it?

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Halyna Strelko, MD

Can oral contraception impact ovarian receptors for FSH and LH?

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Halyna Strelko, MD

Is an AMH of 0.2 to 0.5 at the age of 38-39 a sign of premature ovarian failure?

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Dorothy Walas

My AMH is 3.2, which is very low, and I also have light periods only lasting 2 days. I only had 3 follicles in my last IVF round. Is there anything I can do to increase my follicles? Do you recommend priming or down-regulation for increasing the number of follicles?

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Halyna Strelko, MD

How to tell a child that they are coming from a donor without risking the child considering themselves a designer baby for selfish reasons?

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Viki Peeters

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