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Is a 4CC embryo good?

Category:
3 fertility expert(s) answered this question

What is a good grade for embryo?

Our experts have provided insights into embryo transfer, including how embryos are chosen for transfer using a grading system. When there are many blastocysts available, this system helps select the best ones. However, if options are limited or all embryos are of lower quality, sometimes a C-grade embryo is the only choice for transfer.

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Answer from the fertility expert:
Andrea Sánchez Freire, ReproMed Ireland

4CC is considered the very poor quality of the trophectoderms inner cell mass. So in this case, we’re going to discard those embryos if we have embryos of better quality. Depending on the case, we’ll have a transfer; we can transfer 4CC, but we need to study the patient’s embryo culture to make sure that it’s a good chance for her.

Answer from the fertility expert:
Despina Tzanakaki, Director of IVF and Andrology lab at Aretaieio Hospital

The 4CC embryo is not considered a good embryo. It is well expanded blastocyst on Day 5 with a poor quality of cell mass and poor quality of trophectoderm.

Answer from the fertility expert:
George Koustas, Director of Embryology and Quality Manager, Agora Clinic

Absolutely! A poor embryo can implant.
An embryo that has been graded as CC 3, 4 or even 5 – it means that the embryo has reached the blastocyst stage but it doesn’t have a lot of cells at the group that will make the baby and the group of cells that they would make the placenta. There is sometimes an amazing interaction between the endometrium and a very very poor embryo that will allow the embryo to implant and create a life-birth.
A lot of data have been published showing that grade C embryos and even embryos before that stage which are embryos that they haven’t compacted and yet are able to implant and create a life-birth.

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